Connexin 43: Key roles in the skin

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Fluoxetin Upregulates Connexin 43 Expression in Astrocyte

Introduction: Recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (MS). Molecular target therapy studies in MS have revealed that connexin-43 (Cx43) and Aquaporin-4 (AQP4) contents of astrocytes undergo expression alteration. Fluoxetine had some effects in MS patients unrelated to its known antidep...

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fluoxetin upregulates connexin 43 expression in astrocyte

introduction: recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (ms). molecular target therapy studies in ms have revealed that connexin-43 (cx43) and aquaporin-4 (aqp4) contents of astrocytes undergo expression alteration. fluoxetine had some effects in ms patients unrelated to its known antidep...

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Fluoxetin Upregulates Connexin 43 Expression in Astrocyte

INTRODUCTION Recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (MS). Molecular target therapy studies in MS have revealed that connexin-43 (Cx43) and Aquaporin-4 (AQP4) contents of astrocytes undergo expression alteration. Fluoxetine had some effects in MS patients unrelated to its known antidepr...

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Connexin 43, E-cadherin, beta-catenin and ZO-1 expression, and aberrant methylation of the connexin 43 gene in NSCLC.

BACKGROUND The relationships between connexin 43 (Cx43) expression and clinicopathological factors, epithelial markers, and CpG island methylation in non-small cell lung cancer (NSCLC) are controversial. The aim of this study was to investigate whether the Cx43 expression related with clinicopathological factors, epithelial markers and methylation status of the Cx43 gene. PATIENTS AND METHODS...

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Connexin 43 hemichannels are permeable to ATP.

Astrocytes are electrically nonexcitable cells that communicate by means of Ca(2+) signaling. Long-distance intercellular Ca(2+) waves are initiated by release of ATP and activation of purinergic receptors on nearby cells. Previous studies have implicated connexin 43 (Cx43) in ATP release, but definitive proof that ATP exits through Cx43 hemichannels does not exist. Here, through several altern...

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ژورنال

عنوان ژورنال: Biomedical Reports

سال: 2017

ISSN: 2049-9434,2049-9442

DOI: 10.3892/br.2017.903